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Gene: GNAS (GNAS complex locus) Canis lupus familiaris
Symbol: GNAS
Name: GNAS complex locus
CRRD ID: 12384187
Description: ENCODES a protein that exhibits adenylate cyclase activator activity (ortholog); alkylglycerophosphoethanolamine phosphodiesterase activity (ortholog); alpha-tubulin binding (ortholog); INVOLVED IN adenylate cyclase-activating adrenergic receptor signaling pathway (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); bone development (ortholog); PARTICIPATES IN adenosine signaling pathway; corticotropin-releasing hormone signaling pathway; dopamine signaling pathway via D1 family of receptors; ASSOCIATED WITH acromegaly (ortholog); ACTH Syndrome, Ectopic (ortholog); ACTH-independent macronodular adrenal hyperplasia (ortholog); FOUND IN COPI-coated Golgi to ER transport vesicle (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
Also known as: adenylate cyclase-stimulating G alpha protein; gnas1; GTP-binding regulatory protein alpha subunit exon 1; guanine nucleotide binding protein alpha subunit; guanine nucleotide binding protein, alpha stimulating activity polypeptide 1; guanine nucleotide-binding protein G(s) subunit alpha; stimulatory GTP binding protein
Homo sapiens (human) : GNAS (GNAS complex locus)  HGNC  Alliance
Mus musculus (house mouse) : Gnas (GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gnas (GNAS complex locus)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100990650 (guanine nucleotide-binding protein G(s) subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnas (GNAS complex locus)
Sus scrofa (pig) : GNAS (GNAS complex locus)
Chlorocebus sabaeus (African green monkey) : GNAS (GNAS complex locus)
Heterocephalus glaber (naked mole-rat) : Gnas (GNAS complex locus)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl2443,643,405 - 43,658,657 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12443,643,409 - 43,658,641 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on GNAS
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12384187
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-09-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.