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Gene: RUNX2 (RUNX family transcription factor 2) Canis lupus familiaris
Symbol: RUNX2
Name: RUNX family transcription factor 2
Description: ENCODES a protein that exhibits ATP binding (inferred); bHLH transcription factor binding (inferred); chromatin binding (inferred); INVOLVED IN BMP signaling pathway (inferred); cell maturation (inferred); chondrocyte development (inferred); PARTICIPATES IN fibroblast growth factor signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Bone Fractures (ortholog); cleidocranial dysplasia (ortholog); Cleidocranial Dysplasia, Forme Fruste, Dental Anomalies Only (ortholog); FOUND IN cytoplasm (inferred); nuclear chromatin (inferred); nucleoplasm (inferred); INTERACTS WITH nicotinamide; resveratrol
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: runt-related transcription factor 2; runt related transcription factor 2; runt-related transcription factor 2
Homo sapiens (human) : RUNX2 (RUNX family transcription factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Runx2 (runt related transcription factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Runx2 (RUNX family transcription factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Runx2 (RUNX family transcription factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RUNX2 (RUNX family transcription factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Runx2 (RUNX family transcription factor 2)
Sus scrofa (pig) : RUNX2 (RUNX family transcription factor 2)
Chlorocebus sabaeus (African green monkey) : RUNX2 (RUNX family transcription factor 2)
Heterocephalus glaber (naked mole-rat) : Runx2 (RUNX family transcription factor 2)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl1213,628,539 - 13,840,785 (+)Ensembl
CanFam3.11213,723,535 - 13,842,565 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on RUNX2
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12384713
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.