ALKBH3 (alkB homolog 3, alpha-ketoglutarate dependent dioxygenase) - Chinchilla Research Resource Database
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Gene: ALKBH3 (alkB homolog 3, alpha-ketoglutarate dependent dioxygenase) Canis lupus familiaris
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Symbol: ALKBH3
Name: alkB homolog 3, alpha-ketoglutarate dependent dioxygenase
CRRD ID: 12404163
Description: ENCODES a protein that exhibits 2-oxoglutarate-dependent dioxygenase activity (ortholog); INVOLVED IN DNA repair (ortholog); FOUND IN cytosol (inferred); mitochondrion (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: alkB homolog 3, alpha-ketoglutaratedependent dioxygenase; alkB, alkylation repair homolog 3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3
Orthologs:
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1825,824,877 - 25,899,079 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11825,864,041 - 25,899,226 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
mitochondrion  (IEA)
nucleoplasm  (IEA)

References

Genomics

Comparative Map Data
ALKBH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1825,824,877 - 25,899,079 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11825,864,041 - 25,899,226 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ALKBH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1143,880,811 - 43,920,274 (+)EnsemblGRCh38hg38GRCh38
GRCh381143,880,831 - 43,920,274 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371143,902,357 - 43,941,825 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361143,858,971 - 43,898,389 (+)NCBINCBI36hg18NCBI36
Celera1144,048,227 - 44,087,676 (+)NCBI
Cytogenetic Map11p11.2NCBI
HuRef1143,611,668 - 43,651,108 (+)NCBIHuRef
CHM1_11143,901,678 - 43,940,820 (+)NCBICHM1_1
Alkbh3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39293,810,969 - 93,841,188 (-)NCBI
GRCm38293,980,624 - 94,010,824 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl293,980,550 - 94,010,807 (-)EnsemblGRCm38mm10GRCm38
MGSCv37293,820,791 - 93,850,887 (-)NCBIGRCm37mm9NCBIm37
MGSCv36293,781,391 - 93,811,646 (-)NCBImm8
Celera295,377,139 - 95,407,273 (-)NCBICelera
Cytogenetic Map2E1NCBI
Alkbh3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0382,874,242 - 82,907,467 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl382,874,248 - 82,906,581 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0389,575,451 - 89,608,158 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4378,386,098 - 78,418,432 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1378,282,525 - 78,314,860 (-)NCBI
Celera379,141,033 - 79,172,722 (-)NCBICelera
Cytogenetic Map3q31NCBI
Alkbh3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554223,657,765 - 3,695,409 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554223,660,504 - 3,695,352 (-)NCBIChiLan1.0ChiLan1.0
ALKBH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11144,336,655 - 44,376,058 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,336,655 - 44,376,057 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01143,841,083 - 43,880,608 (+)NCBIMhudiblu_PPA_v0panPan3
Alkbh3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365624,743,595 - 4,777,685 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ALKBH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl218,271,070 - 18,448,292 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1218,408,987 - 18,448,285 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2220,011,987 - 20,048,360 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ALKBH3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl121,462,516 - 21,505,934 (-)Ensembl
ChlSab1.1121,463,744 - 21,505,940 (-)NCBI
Alkbh3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247674,088,173 - 4,139,288 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 5 17 1 2 1 2 6 12 8 10 5
Low 1 5 5 4 5 4 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000010727   ⟹   ENSCAFP00000009944
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1825,864,064 - 25,899,079 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000063920   ⟹   ENSCAFP00000043309
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1825,824,877 - 25,899,079 (-)Ensembl
RefSeq Acc Id: XM_005631094   ⟹   XP_005631151
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11825,864,041 - 25,899,222 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022405292   ⟹   XP_022261000
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11825,864,041 - 25,899,225 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022405293   ⟹   XP_022261001
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11825,864,041 - 25,899,219 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022405294   ⟹   XP_022261002
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11825,869,335 - 25,899,226 (-)NCBI
Sequence:
RefSeq Acc Id: XM_533147   ⟹   XP_533147
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11825,864,041 - 25,899,216 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002615825
RefSeq Status:
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11825,865,129 - 25,899,226 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002615826
RefSeq Status:
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11825,865,129 - 25,899,226 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005631151 (Get FASTA)   NCBI Sequence Viewer  
  XP_022261000 (Get FASTA)   NCBI Sequence Viewer  
  XP_022261001 (Get FASTA)   NCBI Sequence Viewer  
  XP_022261002 (Get FASTA)   NCBI Sequence Viewer  
  XP_533147 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_533147   ⟸   XM_533147
- Peptide Label: isoform X4
- UniProtKB: J9P9A4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005631151   ⟸   XM_005631094
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_022261000   ⟸   XM_022405292
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_022261001   ⟸   XM_022405293
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_022261002   ⟸   XM_022405294
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSCAFP00000043309   ⟸   ENSCAFT00000063920
RefSeq Acc Id: ENSCAFP00000009944   ⟸   ENSCAFT00000010727
Protein Domains
Fe2OG dioxygenase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006657 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCAFP00000009944 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFP00000043309 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010727 ENTREZGENE, UniProtKB/TrEMBL
  ENSCAFT00000063920 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.590 UniProtKB/TrEMBL
InterPro AlkB-like UniProtKB/TrEMBL
  AlkB-like_sf UniProtKB/TrEMBL
  ALKBH3 UniProtKB/TrEMBL
  Oxoglu/Fe-dep_dioxygenase UniProtKB/TrEMBL
KEGG Report cfa:475938 UniProtKB/TrEMBL
NCBI Gene ALKBH3 ENTREZGENE
PANTHER PTHR31212 UniProtKB/TrEMBL
Pfam 2OG-FeII_Oxy_2 UniProtKB/TrEMBL
PROSITE FE2OG_OXY UniProtKB/TrEMBL
UniProt A0A5F4BNM3_CANLF UniProtKB/TrEMBL
  F6UZ53_CANLF UniProtKB/TrEMBL
  J9P9A4 ENTREZGENE
VGNC ID VGNC:37804 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-05-11 ALKBH3  alkB homolog 3, alpha-ketoglutarate dependent dioxygenase  ALKBH3  alkB homolog 3, alpha-ketoglutaratedependent dioxygenase  Symbol and/or name change 19259463 PROVISIONAL
2020-05-04 ALKBH3  alkB homolog 3, alpha-ketoglutaratedependent dioxygenase  ALKBH3  alkB homolog 3, alpha-ketoglutarate dependent dioxygenase  Symbol and/or name change 19259463 PROVISIONAL
2020-04-21 ALKBH3  alkB homolog 3, alpha-ketoglutarate dependent dioxygenase  ALKBH3  alkB homolog 3, alpha-ketoglutaratedependent dioxygenase  Symbol and/or name change 5135510 APPROVED