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Gene: KLHL3 (kelch like family member 3) Canis lupus familiaris
Symbol: KLHL3
Name: kelch like family member 3
Description: ENCODES a protein that exhibits cullin family protein binding (inferred); INVOLVED IN distal tubule morphogenesis (inferred); ion homeostasis (inferred); protein K48-linked ubiquitination (inferred); ASSOCIATED WITH autosomal dominant pseudohypoaldosteronism type 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: kelch-like 3; kelch-like protein 3
Homo sapiens (human) : KLHL3 (kelch like family member 3)  HGNC  Alliance
Mus musculus (house mouse) : Klhl3 (kelch-like 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Klhl3 (kelch-like family member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klhl3 (kelch like family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : KLHL3 (kelch like family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klhl3 (kelch like family member 3)
Sus scrofa (pig) : KLHL3 (kelch like family member 3)
Chlorocebus sabaeus (African green monkey) : KLHL3 (kelch like family member 3)
Heterocephalus glaber (naked mole-rat) : Klhl3 (kelch like family member 3)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1 Ensembl1125,334,241 - 25,443,494 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11125,329,922 - 25,505,281 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on KLHL3
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12408517
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-02-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.