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Gene: NPPB (natriuretic peptide B) Canis lupus familiaris
Symbol: NPPB
Name: natriuretic peptide B
Description: ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); cardiac muscle hypertrophy in response to stress (ortholog); cell growth involved in cardiac muscle cell development (ortholog); PARTICIPATES IN brain natriuretic peptide signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); adult respiratory distress syndrome (ortholog); Animal Disease Models (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); protein-containing complex (ortholog); transport vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: BNP; brain natriuretic peptide; Gamma-brain natriuretic peptide; natriuretic peptide precursor B; Natriuretic peptides B
Homo sapiens (human) : NPPB (natriuretic peptide B)  HGNC  Alliance
Mus musculus (house mouse) : Nppb (natriuretic peptide type B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nppb (natriuretic peptide B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nppb (natriuretic peptide B)
Pan paniscus (bonobo/pygmy chimpanzee) : NPPB (natriuretic peptide B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nppb (natriuretic peptide B)
Sus scrofa (pig) : NPPB (natriuretic peptide B)
Chlorocebus sabaeus (African green monkey) : NPPB (natriuretic peptide B)
Heterocephalus glaber (naked mole-rat) : Nppb (natriuretic peptide B)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1284,395,844 - 84,397,473 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on NPPB
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12423345
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.