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Gene: PDGFB (platelet derived growth factor subunit B) Canis lupus familiaris
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Symbol: PDGFB
Name: platelet derived growth factor subunit B
CRRD ID: 12423670
Description: ENCODES a protein that exhibits growth factor activity (ortholog); identical protein binding (ortholog); platelet-derived growth factor receptor binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); activation of protein kinase activity (ortholog); activation of protein kinase B activity (ortholog); PARTICIPATES IN platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH AIDS Dementia Complex (ortholog); Alzheimer's disease (ortholog); asthma (ortholog); FOUND IN basolateral plasma membrane (ortholog); cell surface (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: PDGF subunit B; PDGF-2; PDGF-B; platelet-derived growth factor B chain; platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog); platelet-derived growth factor subunit B
Orthologs:
Homo sapiens (human) : PDGFB (platelet derived growth factor subunit B)  HGNC  Alliance
Mus musculus (house mouse) : Pdgfb (platelet derived growth factor, B polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pdgfb (platelet derived growth factor subunit B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pdgfb (platelet derived growth factor subunit B)
Pan paniscus (bonobo/pygmy chimpanzee) : PDGFB (platelet derived growth factor subunit B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdgfb (platelet derived growth factor subunit B)
Sus scrofa (pig) : PDGFB (platelet derived growth factor subunit B)
Chlorocebus sabaeus (African green monkey) : PDGFB (platelet derived growth factor subunit B)
Heterocephalus glaber (naked mole-rat) : Pdgfb (platelet derived growth factor subunit B)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1025,798,938 - 25,817,746 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11025,798,877 - 25,819,422 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on PDGFB
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12423670
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-09-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.