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Gene: NPC1 (NPC intracellular cholesterol transporter 1) Canis lupus familiaris
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Symbol: NPC1
Name: NPC intracellular cholesterol transporter 1
Description: ENCODES a protein that exhibits cholesterol binding (ortholog); INVOLVED IN adult walking behavior (ortholog); autophagy (ortholog); cellular response to low-density lipoprotein particle stimulus (ortholog); ASSOCIATED WITH Ataxia (ortholog); atherosclerosis (ortholog); brucellosis (ortholog); FOUND IN endoplasmic reticulum (ortholog); endosome (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Niemann-Pick C1 protein; Niemann-Pick type C1 disease protein
Orthologs:
Homo sapiens (human) : NPC1 (NPC intracellular cholesterol transporter 1)  HGNC  Alliance
Mus musculus (house mouse) : Npc1 (NPC intracellular cholesterol transporter 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Npc1 (NPC intracellular cholesterol transporter 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npc1 (NPC intracellular cholesterol transporter 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NPC1 (NPC intracellular cholesterol transporter 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npc1 (NPC intracellular cholesterol transporter 1)
Sus scrofa (pig) : NPC1 (NPC intracellular cholesterol transporter 1)
Chlorocebus sabaeus (African green monkey) : NPC1 (NPC intracellular cholesterol transporter 1)
Heterocephalus glaber (naked mole-rat) : Npc1 (NPC intracellular cholesterol transporter 1)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl764,760,121 - 64,802,902 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1764,764,941 - 64,802,507 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on NPC1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12435558
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-07-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.