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Gene: F2 (coagulation factor II, thrombin) Ictidomys tridecemlineatus
Symbol: F2
Name: coagulation factor II, thrombin
Description: ENCODES a protein that exhibits enzyme activator activity (ortholog); heparin binding (ortholog); lipopolysaccharide binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); blood coagulation (ortholog); cell surface receptor signaling pathway (ortholog); PARTICIPATES IN acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; aminocaproic acid pharmacodynamics pathway; ASSOCIATED WITH Acquired Angioedema (ortholog); Acute Coronary Syndrome (ortholog); Acute Lung Injury (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: prothrombin
Homo sapiens (human) : F2 (coagulation factor II, thrombin)  HGNC  Alliance
Mus musculus (house mouse) : F2 (coagulation factor II)  MGI  Alliance
Rattus norvegicus (Norway rat) : F2 (coagulation factor II)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F2 (coagulation factor II, thrombin)
Pan paniscus (bonobo/pygmy chimpanzee) : F2 (coagulation factor II, thrombin)
Canis lupus familiaris (dog) : F2 (coagulation factor II, thrombin)
Sus scrofa (pig) : F2 (coagulation factor II, thrombin)
Heterocephalus glaber (naked mole-rat) : F2 (coagulation factor II, thrombin)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
SpeTri2.0NW_0049365622,371,725 - 2,388,617 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on F2
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12439624
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2020-08-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.