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Gene: Itch (itchy E3 ubiquitin protein ligase) Ictidomys tridecemlineatus
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Symbol: Itch
Name: itchy E3 ubiquitin protein ligase
CRRD ID: 12592035
Description: ENCODES a protein that exhibits arrestin family protein binding (ortholog); CXCR chemokine receptor binding (ortholog); ligase activity (ortholog); INVOLVED IN negative regulation of alpha-beta T cell proliferation (ortholog); negative regulation of apoptotic process (ortholog); negative regulation of defense response to virus (ortholog); PARTICIPATES IN Notch signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH cerebellar ataxia (ortholog); long QT syndrome (ortholog); Multisystem Autoimmune Disease with Facial Dysmorphism (ortholog); FOUND IN cell cortex (ortholog); cytoplasm (ortholog); cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin-protein ligase Itchy homolog
Orthologs:
Homo sapiens (human) : ITCH (itchy E3 ubiquitin protein ligase)  HGNC  Alliance
Mus musculus (house mouse) : Itch (itchy, E3 ubiquitin protein ligase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itch (itchy E3 ubiquitin protein ligase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itch (itchy E3 ubiquitin protein ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : ITCH (itchy E3 ubiquitin protein ligase)
Canis lupus familiaris (dog) : ITCH (itchy E3 ubiquitin protein ligase)
Sus scrofa (pig) : ITCH (itchy E3 ubiquitin protein ligase)
Chlorocebus sabaeus (African green monkey) : ITCH (itchy E3 ubiquitin protein ligase)
Heterocephalus glaber (naked mole-rat) : Itch (itchy E3 ubiquitin protein ligase)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365616,140,236 - 6,265,734 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
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Expression


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Nucleotide Sequences
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Additional Information

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More on Itch
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12592035
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2020-08-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.