Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Itch (itchy E3 ubiquitin protein ligase) Ictidomys tridecemlineatus
Symbol: Itch
Name: itchy E3 ubiquitin protein ligase
CRRD ID: 12592035
Description: ENCODES a protein that exhibits arrestin family protein binding (ortholog); CXCR chemokine receptor binding (ortholog); ligase activity (ortholog); INVOLVED IN negative regulation of alpha-beta T cell proliferation (ortholog); negative regulation of apoptotic process (ortholog); negative regulation of defense response to virus (ortholog); PARTICIPATES IN Notch signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH cerebellar ataxia (ortholog); long QT syndrome (ortholog); Multisystem Autoimmune Disease with Facial Dysmorphism (ortholog); FOUND IN cell cortex (ortholog); cytoplasm (ortholog); cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: E3 ubiquitin-protein ligase Itchy homolog
Homo sapiens (human) : ITCH (itchy E3 ubiquitin protein ligase)  HGNC  Alliance
Mus musculus (house mouse) : Itch (itchy, E3 ubiquitin protein ligase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itch (itchy E3 ubiquitin protein ligase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itch (itchy E3 ubiquitin protein ligase)
Pan paniscus (bonobo/pygmy chimpanzee) : ITCH (itchy E3 ubiquitin protein ligase)
Canis lupus familiaris (dog) : ITCH (itchy E3 ubiquitin protein ligase)
Sus scrofa (pig) : ITCH (itchy E3 ubiquitin protein ligase)
Chlorocebus sabaeus (African green monkey) : ITCH (itchy E3 ubiquitin protein ligase)
Heterocephalus glaber (naked mole-rat) : Itch (itchy E3 ubiquitin protein ligase)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
SpeTri2.0NW_0049365616,140,236 - 6,265,734 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Itch
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12592035
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2020-08-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.