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Gene: Irs2 (insulin receptor substrate 2) Ictidomys tridecemlineatus
Symbol: Irs2
Name: insulin receptor substrate 2
CRRD ID: 12663275
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); insulin receptor binding (ortholog); phosphatidylinositol 3-kinase binding (ortholog); INVOLVED IN brain development (ortholog); cellular response to glucose stimulus (ortholog); cellular response to insulin stimulus (ortholog); PARTICIPATES IN erythropoietin signaling pathway; insulin signaling pathway; insulin-like growth factor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Diabetes Mellitus, Experimental (ortholog); Diabetic Nephropathies (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Homo sapiens (human) : IRS2 (insulin receptor substrate 2)  HGNC  Alliance
Mus musculus (house mouse) : Irs2 (insulin receptor substrate 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Irs2 (insulin receptor substrate 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irs2 (insulin receptor substrate 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IRS2 (insulin receptor substrate 2)
Canis lupus familiaris (dog) : IRS2 (insulin receptor substrate 2)
Sus scrofa (pig) : IRS2 (insulin receptor substrate 2)
Chlorocebus sabaeus (African green monkey) : IRS2 (insulin receptor substrate 2)
Heterocephalus glaber (naked mole-rat) : Irs2 (insulin receptor substrate 2)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
SpeTri2.0NW_0049364722,772,187 - 2,796,398 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Irs2
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12663275
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2020-08-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.