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Gene: Irs2 (insulin receptor substrate 2) Ictidomys tridecemlineatus
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Symbol: Irs2
Name: insulin receptor substrate 2
CRRD ID: 12663275
Description: ENCODES a protein that exhibits 14-3-3 protein binding (ortholog); insulin receptor binding (ortholog); phosphatidylinositol 3-kinase binding (ortholog); INVOLVED IN brain development (ortholog); cellular response to glucose stimulus (ortholog); cellular response to insulin stimulus (ortholog); PARTICIPATES IN erythropoietin signaling pathway; insulin signaling pathway; insulin-like growth factor signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Diabetes Mellitus, Experimental (ortholog); Diabetic Nephropathies (ortholog); FOUND IN cytosol (ortholog); plasma membrane (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Orthologs:
Homo sapiens (human) : IRS2 (insulin receptor substrate 2)  HGNC  Alliance
Mus musculus (house mouse) : Irs2 (insulin receptor substrate 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Irs2 (insulin receptor substrate 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irs2 (insulin receptor substrate 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IRS2 (insulin receptor substrate 2)
Canis lupus familiaris (dog) : IRS2 (insulin receptor substrate 2)
Sus scrofa (pig) : IRS2 (insulin receptor substrate 2)
Chlorocebus sabaeus (African green monkey) : IRS2 (insulin receptor substrate 2)
Heterocephalus glaber (naked mole-rat) : Irs2 (insulin receptor substrate 2)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049364722,772,187 - 2,796,398 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Irs2
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12663275
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2020-08-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.