Chrnb4 (cholinergic receptor nicotinic beta 4 subunit) - Chinchilla Research Resource Database
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Gene: Chrnb4 (cholinergic receptor nicotinic beta 4 subunit) Ictidomys tridecemlineatus
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Symbol: Chrnb4
Name: cholinergic receptor nicotinic beta 4 subunit
CRRD ID: 12690720
Description: ENCODES a protein that exhibits acetylcholine binding (ortholog); acetylcholine receptor activity (ortholog); acetylcholine-gated cation-selective channel activity (ortholog); INVOLVED IN action potential (ortholog); behavioral response to nicotine (ortholog); locomotory behavior (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Lung Neoplasms (ortholog); Tobacco Use Disorder (ortholog); FOUND IN acetylcholine-gated channel complex (ortholog); cholinergic synapse (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: neuronal acetylcholine receptor subunit beta-4
Orthologs:
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647136,408,471 - 36,425,571 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Chrnb4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493647136,408,471 - 36,425,571 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHRNB4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1578,624,111 - 78,727,754 (-)EnsemblGRCh38hg38GRCh38
GRCh381578,623,282 - 78,655,586 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371578,916,636 - 78,933,587 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361576,703,691 - 76,720,642 (-)NCBINCBI36hg18NCBI36
Build 341576,703,690 - 76,720,642NCBI
Celera1555,852,898 - 55,869,734 (-)NCBI
Cytogenetic Map15q25.1NCBI
HuRef1555,674,500 - 55,691,566 (-)NCBIHuRef
CHM1_11579,035,191 - 79,052,089 (-)NCBICHM1_1
Chrnb4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39954,935,438 - 54,956,236 (-)NCBI
GRCm38955,028,154 - 55,048,953 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl955,028,154 - 55,048,779 (-)EnsemblGRCm38mm10GRCm38
MGSCv37954,875,963 - 54,896,351 (-)NCBIGRCm37mm9NCBIm37
MGSCv36954,826,293 - 54,846,681 (-)NCBImm8
Celera952,271,558 - 52,291,872 (-)NCBICelera
Cytogenetic Map9BNCBI
Chrnb4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0859,610,489 - 59,629,073 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl859,609,693 - 59,629,133 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0858,192,375 - 58,210,959 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4858,586,961 - 58,605,545 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1858,605,220 - 58,624,659 (-)NCBI
Celera854,902,516 - 54,921,100 (-)NCBICelera
Cytogenetic Map8q24NCBI
RH 3.4 Map8614.4RGD
Chrnb4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554501,013,607 - 1,030,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554501,013,897 - 1,030,232 (-)NCBIChiLan1.0ChiLan1.0
CHRNB4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11576,515,683 - 76,532,905 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1576,515,455 - 76,532,712 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01557,552,697 - 57,570,828 (-)NCBIMhudiblu_PPA_v0panPan3
CHRNB4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1338,312,173 - 38,328,341 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11338,312,537 - 38,327,242 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CHRNB4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1747,338,819 - 47,359,064 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2752,808,908 - 52,829,172 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CHRNB4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl264,701,321 - 4,719,319 (+)Ensembl
ChlSab1.1264,700,217 - 4,717,363 (+)NCBI
Chrnb4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248942,305,815 - 2,322,264 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005316846   ⟹   XP_005316903
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_00493647136,408,471 - 36,425,571 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728733   ⟹   XP_021584408
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_00493647136,412,694 - 36,425,571 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728748   ⟹   XP_021584423
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_00493647136,410,880 - 36,425,571 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005316903 (Get FASTA)   NCBI Sequence Viewer  
  XP_021584408 (Get FASTA)   NCBI Sequence Viewer  
  XP_021584423 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005316903   ⟸   XM_005316846
- Peptide Label: isoform X2
- UniProtKB: I3MTT5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021584423   ⟸   XM_021728748
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021584408   ⟸   XM_021728733
- Peptide Label: isoform X1
- Sequence:
Protein Domains
Neur_chan_LBD   Neur_chan_memb


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000028304 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000015530 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000031207 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000031841 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023765 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOT00000038053 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOT00000038161 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.70.170.10 UniProtKB/TrEMBL
InterPro Neur_chan_lig-bd UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/TrEMBL
  Neur_channel UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/TrEMBL
  Nicotinic_acetylcholine_rcpt UniProtKB/TrEMBL
NCBI Gene Chrnb4 ENTREZGENE
PANTHER PTHR18945 UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/TrEMBL
PRINTS NICOTINICR UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/TrEMBL
  SSF90112 UniProtKB/TrEMBL
TIGRFAMs LIC UniProtKB/TrEMBL
UniProt A0A287DCB0_ICTTR UniProtKB/TrEMBL
  A0A287DEA6_ICTTR UniProtKB/TrEMBL
  I3MTT5 ENTREZGENE, UniProtKB/TrEMBL