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Gene: Sirt6 (sirtuin 6) Ictidomys tridecemlineatus
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Symbol: Sirt6
Name: sirtuin 6
Description: ENCODES a protein that exhibits chromatin binding (ortholog); NAD(P)+-protein-arginine ADP-ribosyltransferase activity (ortholog); NAD-dependent histone deacetylase activity (H3-K9 specific) (ortholog); INVOLVED IN base-excision repair (ortholog); glucose homeostasis (ortholog); negative regulation of cell population proliferation (ortholog); PARTICIPATES IN histone modification pathway; Sirtuin mediated pathway; ASSOCIATED WITH amenorrhea (ortholog); Cardiomegaly (ortholog); fatty liver disease (ortholog); FOUND IN chromosome, subtelomeric region (ortholog); cytoplasm (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: NAD-dependent protein deacetylase sirtuin-6
Orthologs:
Homo sapiens (human) : SIRT6 (sirtuin 6)  HGNC  Alliance
Mus musculus (house mouse) : Sirt6 (sirtuin 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sirt6 (sirtuin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sirt6 (sirtuin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SIRT6 (sirtuin 6)
Canis lupus familiaris (dog) : SIRT6 (sirtuin 6)
Sus scrofa (pig) : SIRT6 (sirtuin 6)
Chlorocebus sabaeus (African green monkey) : SIRT6 (sirtuin 6)
Heterocephalus glaber (naked mole-rat) : Sirt6 (sirtuin 6)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365882,387,162 - 2,394,066 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations

Genomics

Comparative Map Data

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Sirt6
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 12713974
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2020-08-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.