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Gene: Ifnar1em1 (interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 1) Rattus norvegicus
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Symbol: Ifnar1em1
Name: interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 1
Description: An Ifnar1 target region in exon 4, encoding the IFN-binding domain, was disrupted in the genome of the LEW.1WR1 rat using the CRISPR-Cas9 method. The resulting mutant carries a 81-bp deletion in the exon 4 of Ifnar1 gene.
ASSOCIATED WITH decreased susceptibility to autoimmune diabetes; increased susceptibility to viral infection induced morbidity/mortality; insulitis; ASSOCIATED WITH Cardiovirus Infections; Diabetes Mellitus, Experimental
Type: allele  of Ifnar1  
Also known as: Ifnar1em1
Is Marker For: Strains:   LEW.1WR1-Ifnar1em1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position: No map positions available.


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Additional Information

 
More on Ifnar1em1
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CRRD Object Information
CRRD ID: 12910495
Created: 2017-06-16
Species: Rattus norvegicus
Last Modified: 2017-06-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.