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Gene: Pon3 (paraoxonase 3) Rattus norvegicus
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Symbol: Pon3
Name: paraoxonase 3
Description: Exhibits 3,4-dihydrocoumarin hydrolase activity and arylesterase activity. Involved in coumarin catabolic process and phenylacetate catabolic process. Localizes to the extracellular space and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in Alzheimer's disease; amyotrophic lateral sclerosis; and atherosclerosis. Orthologous to human PON3 (paraoxonase 3); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC95026; serum paraoxonase/lactonase 3
Orthologs:
Homo sapiens (human) : PON3 (paraoxonase 3)  HGNC  Alliance
Mus musculus (house mouse) : Pon3 (paraoxonase 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pon3 (paraoxonase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PON3 (paraoxonase 3)
Canis lupus familiaris (dog) : PON3 (paraoxonase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pon3 (paraoxonase 3)
Sus scrofa (pig) : PON3 (paraoxonase 3)
more info ...
Allele / Splice: Pon3em1Mcwi  
Genetic Models: SS-Pon3em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0430,311,981 - 30,338,679 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0430,218,888 - 30,245,586 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4430,000,505 - 30,027,203 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1430,039,834 - 30,066,533 (-)NCBI
Celera428,883,809 - 28,910,507 (-)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Pon3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1302965
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.