Gene: Lag3 (lymphocyte activating 3) Rattus norvegicus
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Symbol: Lag3
Name: lymphocyte activating 3
Description: Predicted to have MHC class II protein binding activity and transmembrane signaling receptor activity; predicted to be involved in several processes, including cell surface receptor signaling pathway, negative regulation of T cell activation, and negative regulation of interleukin-2 biosynthetic process; predicted to localize to the external side of plasma membrane; orthologous to human LAG3 (lymphocyte activating 3); INTERACTS WITH bisphenol A; endosulfan; orphenadrine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD223; LAG-3; LOC297596; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; MGC108901
Orthologs:
Homo sapiens (human) : LAG3 (lymphocyte activating 3)  HGNC  Alliance
Mus musculus (house mouse) : Lag3 (lymphocyte-activation gene 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lag3 (lymphocyte activating 3)
Pan paniscus (bonobo/pygmy chimpanzee) : LAG3 (lymphocyte activating 3)
Canis lupus familiaris (dog) : LAG3 (lymphocyte activating 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lag3 (lymphocyte activating 3)
Sus scrofa (pig) : LAG3 (lymphocyte activating 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04157,425,644 - 157,433,700 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,443,422 - 224,451,485 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44161,031,506 - 161,039,255 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14161,276,441 - 161,284,191 (-)NCBI
Celera4146,449,946 - 146,457,685 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Lag3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1302990
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.