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Gene: Tomm70 (translocase of outer mitochondrial membrane 70) Rattus norvegicus
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Symbol: Tomm70
Name: translocase of outer mitochondrial membrane 70
Description: Involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development; protein targeting to mitochondrion; and response to thyroxine. Localizes to the integral component of mitochondrial outer membrane and mitochondrial outer membrane translocase complex. Used to study congestive heart failure. Biomarker of hypothyroidism. Orthologous to human TOMM70 (translocase of outer mitochondrial membrane 70); PARTICIPATES IN alpha-helical insertion pathway of mitochondrial protein import; beta-barrel pathway of mitochondrial protein import; carrier pathway of mitochondrial protein import.; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC112570; mitochondrial import receptor subunit TOM70; mitochondrial precursor proteins import receptor; TOM70; Tomm70a; translocase of outer membrane 70 kDa subunit; translocase of outer mitochondrial membrane 70 homolog A; translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae); translocase of outer mitochondrial membrane 70 homolog A (yeast); translocase of outer mitochondrial membrane protein 70
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01145,477,053 - 45,511,409 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01148,669,804 - 48,706,365 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41144,302,535 - 44,341,250 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11144,360,417 - 44,398,702 (-)NCBI
Celera1143,168,344 - 43,206,551 (-)NCBICelera
Cytogenetic Map11q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tomm70
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1303049
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.