Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tyrobp (transmembrane immune signaling adaptor Tyrobp) Rattus norvegicus
Analyze
Symbol: Tyrobp
Name: transmembrane immune signaling adaptor Tyrobp
Description: Predicted to have identical protein binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including myeloid cell activation involved in immune response; regulation of cytokine production; and regulation of lymphocyte activation. Predicted to localize to cell and cell surface. Human ortholog(s) of this gene implicated in Nasu-Hakola disease. Orthologous to human TYROBP (transmembrane immune signaling adaptor TYROBP); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DAP12; DNAX-activation protein 12; Karap; killer cell activating receptor-associated protein; LOC361537; Tyro protein tyrosine kinase binding protein; TYRO protein tyrosine kinase-binding protein
Orthologs:
Homo sapiens (human) : TYROBP (transmembrane immune signaling adaptor TYROBP)  HGNC  Alliance
Mus musculus (house mouse) : Tyrobp (TYRO protein tyrosine kinase binding protein)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tyrobp (transmembrane immune signaling adaptor TYROBP)
Pan paniscus (bonobo/pygmy chimpanzee) : TYROBP (transmembrane immune signaling adaptor TYROBP)
Canis lupus familiaris (dog) : TYROBP (transmembrane immune signaling adaptor TYROBP)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tyrobp (transmembrane immune signaling adaptor TYROBP)
Sus scrofa (pig) : TYROBP (transmembrane immune signaling adaptor TYROBP)
Chlorocebus sabaeus (African green monkey) : TYROBP (transmembrane immune signaling adaptor TYROBP)
Heterocephalus glaber (naked mole-rat) : Tyrobp (transmembrane immune signaling adaptor TYROBP)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0188,875,370 - 88,879,305 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,875,375 - 88,879,303 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,031,123 - 90,034,976 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,365,371 - 85,369,224 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1185,443,481 - 85,447,330 (+)NCBI
Celera180,045,174 - 80,049,027 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tyrobp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1303081
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.