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Gene: Nop53 (NOP53 ribosome biogenesis factor) Rattus norvegicus
Symbol: Nop53
Name: NOP53 ribosome biogenesis factor
Description: Predicted to have 5S rRNA binding activity; identical protein binding activity; and p53 binding activity. Predicted to be involved in several processes, including protein localization to nucleus; regulation of cellular protein metabolic process; and regulation of intracellular signal transduction. Predicted to colocalize with rDNA heterochromatin. Orthologous to human NOP53 (NOP53 ribosome biogenesis factor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; aristolochic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glioma tumor suppressor candidate region gene 2; glioma tumor suppressor candidate region gene 2 protein; Gltscr2; LOC292624; preS1 binding protein
Homo sapiens (human) : NOP53 (NOP53 ribosome biogenesis factor)  HGNC  Alliance
Mus musculus (house mouse) : Nop53 (NOP53 ribosome biogenesis factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nop53 (NOP53 ribosome biogenesis factor)
Pan paniscus (bonobo/pygmy chimpanzee) : NOP53 (NOP53 ribosome biogenesis factor)
Canis lupus familiaris (dog) : NOP53 (NOP53 ribosome biogenesis factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nop53 (NOP53 ribosome biogenesis factor)
Sus scrofa (pig) : NOP53 (NOP53 ribosome biogenesis factor)
Chlorocebus sabaeus (African green monkey) : NOP53 (NOP53 ribosome biogenesis factor)
Heterocephalus glaber (naked mole-rat) : Nop53 (NOP53 ribosome biogenesis factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0177,836,522 - 77,843,991 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl177,836,196 - 77,844,189 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,101,202 - 79,108,671 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,281,104 - 76,288,571 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1176,359,212 - 76,366,682 (-)NCBI
Celera171,119,638 - 71,127,111 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nop53
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1303085
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.