Gene: Gsn (gelsolin) Rattus norvegicus
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Symbol: Gsn
Name: gelsolin
Description: Exhibits actin binding activity; involved in several processes, including actin filament severing, actin polymerization or depolymerization, and aging; localizes to several cellular components, including the actin cytoskeleton, extracellular space, and myelin sheath; predicted to colocalize with the focal adhesion and nucleus; biomarker of hypothyroidism and lung disease; orthologous to human GSN (gelsolin); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; N-cadherin signaling pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: actin-depolymerizing factor; ADF; brevin; MGC95032
Orthologs:
Homo sapiens (human) : GSN (gelsolin)  HGNC  Alliance
Mus musculus (house mouse) : Gsn (gelsolin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gsn (gelsolin)
Pan paniscus (bonobo/pygmy chimpanzee) : GSN (gelsolin)
Canis lupus familiaris (dog) : GSN (gelsolin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsn (gelsolin)
Sus scrofa (pig) : GSN (gelsolin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0314,456,106 - 14,508,922 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0319,773,655 - 19,826,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4314,360,245 - 14,386,313 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1314,256,616 - 14,282,685 (+)NCBI
Celera313,325,045 - 13,351,501 (+)NCBICelera
Cytogenetic Map3p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gsn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1303089
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.