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Gene: Vars2 (valyl-tRNA synthetase 2, mitochondrial) Rattus norvegicus
Symbol: Vars2
Name: valyl-tRNA synthetase 2, mitochondrial
CRRD ID: 1303122
Description: Predicted to have valine-tRNA ligase activity. Predicted to be involved in valyl-tRNA aminoacylation. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 20. Orthologous to human VARS2 (valyl-tRNA synthetase 2, mitochondrial); PARTICIPATES IN aminoacyl-tRNA biosynthetic pathway; valine, leucine and isoleucine biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA1885; valine--tRNA ligase; valine--tRNA ligase, mitochondrial; valRS; valyl-tRNA synthetase 2, mitochondrial (putative); valyl-tRNA synthetase 2-like; valyl-tRNA synthetase, mitochondrial; valyl-tRNA synthetase-like; Vars2l; Varsl
Homo sapiens (human) : VARS2 (valyl-tRNA synthetase 2, mitochondrial)  HGNC  Alliance
Mus musculus (house mouse) : Vars2 (valyl-tRNA synthetase 2, mitochondrial)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vars2 (valyl-tRNA synthetase 2, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : VARS2 (valyl-tRNA synthetase 2, mitochondrial)
Canis lupus familiaris (dog) : VARS2 (valyl-tRNA synthetase 2, mitochondrial)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vars2 (valyl-tRNA synthetase 2, mitochondrial)
Sus scrofa (pig) : VARS2 (valyl-tRNA synthetase 2, mitochondrial)
Chlorocebus sabaeus (African green monkey) : VARS2 (valyl-tRNA synthetase 2, mitochondrial)
Heterocephalus glaber (naked mole-rat) : Vars2 (valyl-tRNA synthetase 2, mitochondrial)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0203,588,462 - 3,599,514 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,588,497 - 3,599,514 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0205,685,445 - 5,696,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,228,063 - 3,238,909 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,228,289 - 3,239,136 (+)NCBI
Celera20502,836 - 513,682 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Vars2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1303122
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.