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Gene: Spint1 (serine peptidase inhibitor, Kunitz type 1) Rattus norvegicus
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Symbol: Spint1
Name: serine peptidase inhibitor, Kunitz type 1
Description: Exhibits serine-type endopeptidase inhibitor activity. Involved in cellular response to BMP stimulus; negative regulation of neural precursor cell proliferation; and positive regulation of glial cell differentiation. Localizes to plasma membrane. Biomarker of liver cirrhosis. Orthologous to human SPINT1 (serine peptidase inhibitor, Kunitz type 1); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: HAI-1; hepatocyte growth factor activator inhibitor 1; hepatocyte growth factor activator inhibitor-1; kunitz-type protease inhibitor 1; serine protease inhibitor, Kunitz type 1
Orthologs:
Homo sapiens (human) : SPINT1 (serine peptidase inhibitor, Kunitz type 1)  HGNC  Alliance
Mus musculus (house mouse) : Spint1 (serine protease inhibitor, Kunitz type 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spint1 (serine peptidase inhibitor, Kunitz type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SPINT1 (serine peptidase inhibitor, Kunitz type 1)
Canis lupus familiaris (dog) : SPINT1 (serine peptidase inhibitor, Kunitz type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spint1 (serine peptidase inhibitor, Kunitz type 1)
Sus scrofa (pig) : SPINT1 (serine peptidase inhibitor, Kunitz type 1)
Chlorocebus sabaeus (African green monkey) : SPINT1 (serine peptidase inhibitor, Kunitz type 1)
Heterocephalus glaber (naked mole-rat) : Spint1 (serine peptidase inhibitor, Kunitz type 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03111,049,132 - 111,061,991 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3111,049,118 - 111,062,011 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03117,599,717 - 117,612,635 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,757,666 - 105,770,345 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13105,654,093 - 105,666,772 (+)NCBI
Celera3105,144,668 - 105,157,338 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Spint1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1303138
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.