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Gene: Ppid (peptidylprolyl isomerase D) Rattus norvegicus
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Symbol: Ppid
Name: peptidylprolyl isomerase D
Description: Exhibits cyclosporin A binding activity; enzyme binding activity; and peptidyl-prolyl cis-trans isomerase activity. Involved in several processes, including negative regulation of apoptotic process; protein peptidyl-prolyl isomerization; and regulation of mitochondrial membrane potential. Localizes to the mitochondrion. Orthologous to human PPID (peptidylprolyl isomerase D); PARTICIPATES IN estrogen signaling pathway; calcium/calcium-mediated signaling pathway; Huntington's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin D; cyclophilin-40; Cyp-40; CypD; MGC93768; peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D (cyclophilin D); PPIase; PPIase D; rotamase; rotamase D
Orthologs:
Homo sapiens (human) : PPID (peptidylprolyl isomerase D)  HGNC  Alliance
Mus musculus (house mouse) : Ppid (peptidylprolyl isomerase D (cyclophilin D))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppid (peptidylprolyl isomerase D)
Pan paniscus (bonobo/pygmy chimpanzee) : PPID (peptidylprolyl isomerase D)
Canis lupus familiaris (dog) : PPID (peptidylprolyl isomerase D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppid (peptidylprolyl isomerase D)
Sus scrofa (pig) : PPID (peptidylprolyl isomerase D)
more info ...
Related Pseudogenes: Ppid-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: This gene encodes a 370 aa protein that is found in the cytoplasm. In some databases, it has been labeled incorrectly as 'cyclophilin D'. This same name has also been applied to a different protein, found in the mitochondrion, which is represented by GeneID 282819, Ppif. [13 Feb 2013]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02178,354,830 - 178,366,843 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2178,354,890 - 178,366,685 (+)Ensembl
Rnor_5.02197,690,283 - 197,702,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42170,995,919 - 171,007,932 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12170,946,024 - 170,958,036 (+)NCBI
Celera2158,824,413 - 158,836,426 (+)NCBICelera
Cytogenetic Map2q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ppid
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1303174
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.