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Gene: Knstrn (kinetochore-localized astrin/SPAG5 binding protein) Rattus norvegicus
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Symbol: Knstrn
Name: kinetochore-localized astrin/SPAG5 binding protein
CRRD ID: 1303240
Description: Predicted to have microtubule plus-end binding activity and protein homodimerization activity. Predicted to be involved in several processes, including cellular response to epidermal growth factor stimulus; mitotic sister chromatid segregation; and regulation of attachment of spindle microtubules to kinetochore. Predicted to localize to several cellular components, including kinetochore; microtubule cytoskeleton; and ruffle. Human ortholog(s) of this gene implicated in actinic keratosis and skin squamous cell carcinoma. Orthologous to human KNSTRN (kinetochore localized astrin (SPAG5) binding protein); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C15orf23; kinastrin; kinetochore-localized astrin-binding protein; kinetochore-localized astrin/SPAG5-binding protein; MGC94986; putative TRAF4-associated factor 1; SKAP; small kinetochore-associated protein; TRAF4 associated factor 1; TRAF4-associated factor 1; Traf4af1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03110,618,256 - 110,638,024 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3110,618,298 - 110,638,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03117,157,742 - 117,177,511 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43105,322,270 - 105,341,927 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13105,218,697 - 105,238,354 (+)NCBI
Celera3104,715,313 - 104,733,650 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Knstrn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1303240
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.