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Gene: Map3k3 (mitogen activated protein kinase kinase kinase 3) Rattus norvegicus
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Symbol: Map3k3
Name: mitogen activated protein kinase kinase kinase 3
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular protein modification process; negative regulation of cellular senescence; and positive regulation of protein phosphorylation. Predicted to localize to the cytoplasm. Orthologous to human MAP3K3 (mitogen-activated protein kinase kinase kinase 3); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; Erk5 MAPK signaling pathway; interleukin-1 signaling pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC303604; mitogen-activated protein kinase kinase kinase 3
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01094,280,703 - 94,349,372 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01094,029,306 - 94,098,042 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41095,482,303 - 95,551,065 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11095,496,690 - 95,565,451 (+)NCBI
Celera1089,696,294 - 89,764,939 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Map3k3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304575
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.