Gene: Ago4 (argonaute RISC component 4) Rattus norvegicus
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Symbol: Ago4
Name: argonaute RISC component 4
Description: Predicted to have double-stranded RNA binding activity, miRNA binding activity, and single-stranded RNA binding activity; predicted to be involved in several processes, including RNA metabolic process, meiotic nuclear division, and negative regulation of macromolecule metabolic process; predicted to localize to several cellular components, including the RISC complex, RISC-loading complex, and cytoplasm; orthologous to human AGO4 (argonaute RISC catalytic component 4); PARTICIPATES IN microRNA pathway; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; endosulfan.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: argonaute 4, RISC catalytic component; argonaute RISC catalytic component 4; Eif2c4; eukaryotic translation initiation factor 2C, 4; LOC298533; protein argonaute-4
Orthologs:
Homo sapiens (human) : AGO4 (argonaute RISC component 4)  HGNC  Alliance
Mus musculus (house mouse) : Ago4 (argonaute RISC catalytic subunit 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago4 (argonaute RISC catalytic component 4)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO4 (argonaute RISC catalytic component 4)
Canis lupus familiaris (dog) : AGO4 (argonaute RISC component 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ago4 (argonaute RISC catalytic component 4)
Sus scrofa (pig) : AGO4 (argonaute RISC catalytic component 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05144,501,875 - 144,557,165 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05148,269,991 - 148,328,500 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45145,857,594 - 145,902,950 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15145,866,645 - 145,932,628 (-)NCBI
Celera5137,279,250 - 137,322,143 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ago4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304583
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.