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Gene: Rasgrp3 (RAS guanyl releasing protein 3) Rattus norvegicus
Symbol: Rasgrp3
Name: RAS guanyl releasing protein 3
Description: Predicted to have GTPase activator activity; Ras guanyl-nucleotide exchange factor activity; and kinase binding activity. Predicted to be involved in Ras protein signal transduction and regulation of GTPase activity. Predicted to localize to guanyl-nucleotide exchange factor complex and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human RASGRP3 (RAS guanyl releasing protein 3); PARTICIPATES IN B cell receptor signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
Also known as: LOC313874; RAS guanyl releasing protein 3 (calcium and DAG-regulated); ras guanyl-releasing protein 3; RAS, guanyl releasing protein 3
Homo sapiens (human) : RASGRP3 (RAS guanyl releasing protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Rasgrp3 (RAS, guanyl releasing protein 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rasgrp3 (RAS guanyl releasing protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : RASGRP3 (RAS guanyl releasing protein 3)
Canis lupus familiaris (dog) : RASGRP3 (RAS guanyl releasing protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rasgrp3 (RAS guanyl releasing protein 3)
Sus scrofa (pig) : RASGRP3 (RAS guanyl releasing protein 3)
Chlorocebus sabaeus (African green monkey) : RASGRP3 (RAS guanyl releasing protein 3)
Heterocephalus glaber (naked mole-rat) : Rasgrp3 (RAS guanyl releasing protein 3)
more info ...
Allele / Splice: Rasgrp3em1Mcwi   Rasgrp3em3Mcwi  
Genetic Models: SS-Rasgrp3em1Mcwi SS-Rasgrp3em3Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0621,072,634 - 21,171,619 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl621,072,634 - 21,135,880 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0630,966,364 - 31,065,175 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4619,808,453 - 19,871,923 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1619,815,248 - 19,848,714 (-)NCBI
Celera619,464,356 - 19,527,205 (-)NCBICelera
Cytogenetic Map6q12-q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Rasgrp3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304612
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.