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Gene: Ago1 (argonaute RISC component 1) Rattus norvegicus
Symbol: Ago1
Name: argonaute RISC component 1
Description: Predicted to have RNA polymerase II complex binding activity and nucleic acid binding activity. Predicted to be involved in several processes, including RNA metabolic process; gene silencing by miRNA; and positive regulation of NIK/NF-kappaB signaling. Predicted to localize to several cellular components, including P-body; RISC complex; and RISC-loading complex. Orthologous to human AGO1 (argonaute RISC component 1); PARTICIPATES IN microRNA pathway; INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: argonaute 1, RISC catalytic component; argonaute RISC catalytic component 1; Eif2c1; eukaryotic translation initiation factor 2C, 1; LOC313594; protein argonaute-1
Homo sapiens (human) : AGO1 (argonaute RISC component 1)  HGNC  Alliance
Mus musculus (house mouse) : Ago1 (argonaute RISC catalytic subunit 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ago1 (argonaute RISC component 1)
Pan paniscus (bonobo/pygmy chimpanzee) : AGO1 (argonaute RISC component 1)
Canis lupus familiaris (dog) : AGO1 (argonaute RISC component 1)
Sus scrofa (pig) : AGO1 (argonaute RISC component 1)
Chlorocebus sabaeus (African green monkey) : AGO1 (argonaute RISC component 1)
Heterocephalus glaber (naked mole-rat) : Ago1 (argonaute RISC component 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.05144,444,390 - 144,479,430 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5144,448,792 - 144,479,306 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05148,214,328 - 148,246,407 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45145,797,436 - 145,829,516 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15145,806,727 - 145,840,972 (-)NCBI
Celera5137,218,551 - 137,248,255 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Ago1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304619
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.