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Gene: Traf3 (Tnf receptor-associated factor 3) Rattus norvegicus
Symbol: Traf3
Name: Tnf receptor-associated factor 3
Description: Predicted to have enzyme binding activity; tumor necrosis factor receptor binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of NF-kappaB transcription factor activity; regulation of defense response; and regulation of intracellular signal transduction. Predicted to localize to CD40 receptor complex and cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human TRAF3 (TNF receptor associated factor 3); PARTICIPATES IN Toll-like receptor signaling pathway; hepatitis C pathway; Retinoic acid-inducible gene (RIG) I-like receptor signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: LOC362788
Homo sapiens (human) : TRAF3 (TNF receptor associated factor 3)  HGNC  Alliance
Mus musculus (house mouse) : Traf3 (TNF receptor-associated factor 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Traf3 (TNF receptor associated factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TRAF3 (TNF receptor associated factor 3)
Canis lupus familiaris (dog) : TRAF3 (TNF receptor associated factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Traf3 (TNF receptor associated factor 3)
Sus scrofa (pig) : TRAF3 (TNF receptor associated factor 3)
Chlorocebus sabaeus (African green monkey) : TRAF3 (TNF receptor associated factor 3)
Heterocephalus glaber (naked mole-rat) : Traf3 (TNF receptor associated factor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.06135,610,698 - 135,720,247 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,610,743 - 135,718,564 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,694,225 - 144,804,047 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,925,375 - 136,027,270 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16136,003,658 - 136,028,793 (+)NCBI
Celera6127,764,032 - 127,864,462 (+)NCBICelera
Cytogenetic Map6q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Traf3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304633
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.