Gene: Arhgef2 (Rho/Rac guanine nucleotide exchange factor 2) Rattus norvegicus
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Symbol: Arhgef2
Name: Rho/Rac guanine nucleotide exchange factor 2
Description: Predicted to have Rac guanyl-nucleotide exchange factor activity, microtubule binding activity, and transcription factor binding activity; predicted to be involved in several processes, including generation of neurons, negative regulation of cell death, and negative regulation of cellular component organization; localizes to the glutamatergic synapse and postsynaptic density, intracellular component; orthologous to human ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2); PARTICIPATES IN Reelin signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; beta-naphthoflavone; cisplatin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GEF-H1; guanine nucleotide exchange factor H1; LOC310635; MGC95068; rho guanine nucleotide exchange factor 2; rho/rac guanine nucleotide exchange factor (GEF) 2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02187,964,100 - 188,022,847 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02207,366,791 - 207,423,801 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42180,748,313 - 180,775,656 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12180,698,418 - 180,725,761 (+)NCBI
Celera2168,035,282 - 168,062,671 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Arhgef2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304659
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.