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Gene: Atg7 (autophagy related 7) Rattus norvegicus
Symbol: Atg7
Name: autophagy related 7
Description: Predicted to have protein homodimerization activity; transcription factor binding activity; and ubiquitin-like modifier activating enzyme activity. Involved in several processes, including aging; cellular response to morphine; and negative regulation of mitochondrial DNA replication. Localizes to the axon. Used to study malignant glioma. Biomarker of hypertension; myocardial infarction; neurodegenerative disease; and paraplegia. Orthologous to human ATG7 (autophagy related 7); PARTICIPATES IN autophagy pathway; mitochondrial autophagy pathway; INTERACTS WITH 2,4-dinitrotoluene; 2-methoxyethanol; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
Also known as: APG7-like; Apg7l; ATG12-activating enzyme E1 ATG7; ATG7 autophagy related 7 homolog; ATG7 autophagy related 7 homolog (S. cerevisiae); autophagy 7-like; autophagy 7-like (S. cerevisiae); autophagy related 7 homolog; autophagy related 7 homolog (S. cerevisiae); autophagy-related 7; autophagy-related 7 (yeast); autophagy-related protein 7; LOC312647; ubiquitin-activating enzyme E1-like protein; ubiquitin-like modifier-activating enzyme ATG7
Homo sapiens (human) : ATG7 (autophagy related 7)  HGNC  Alliance
Mus musculus (house mouse) : Atg7 (autophagy related 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atg7 (autophagy related 7)
Pan paniscus (bonobo/pygmy chimpanzee) : ATG7 (autophagy related 7)
Canis lupus familiaris (dog) : ATG7 (autophagy related 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atg7 (autophagy related 7)
Sus scrofa (pig) : ATG7 (autophagy related 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04146,570,113 - 146,777,093 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04209,861,459 - 210,067,618 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44150,814,706 - 150,992,704 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14151,059,546 - 151,153,422 (+)NCBI
Celera4136,643,475 - 136,821,326 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Atg7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304817
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.