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Gene: Mrtfa (myocardin related transcription factor A) Rattus norvegicus
Symbol: Mrtfa
Name: myocardin related transcription factor A
Description: Predicted to have several functions, including DNA-binding transcription factor activity; actin monomer binding activity; and leucine zipper domain binding activity. Involved in regulation of transcription by RNA polymerase II. Localizes to the nucleus. Human ortholog(s) of this gene implicated in megakaryocytic leukemia. Orthologous to human MRTFA (myocardin related transcription factor A); INTERACTS WITH (RS)-amphetamine; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Also known as: basic, SAP, and coiled-coil domain containing protein; BSAC; FLMKL1; LOC315151; megakaryoblastic leukemia (translocation) 1; megakaryoblastic leukemia 1 met; MELODY; MKL/myocardin-like protein 1; Mkl1; MKL1-elongated derivative of yield protein; MKL1met; Mrtf-a
Homo sapiens (human) : MRTFA (myocardin related transcription factor A)  HGNC  Alliance
Mus musculus (house mouse) : Mrtfa (myocardin related transcription factor A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mrtfa (myocardin related transcription factor A)
Pan paniscus (bonobo/pygmy chimpanzee) : MRTFA (myocardin related transcription factor A)
Canis lupus familiaris (dog) : MRTFA (myocardin related transcription factor A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mrtfa (myocardin related transcription factor A)
Sus scrofa (pig) : MRTFA (myocardin related transcription factor A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.07122,233,196 - 122,403,661 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07122,217,533 - 122,387,766 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,306,220 - 119,415,012 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17119,340,456 - 119,511,326 (-)NCBI
Celera7108,866,997 - 109,036,998 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Mrtfa
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304873
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.