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Gene: Mrtfa (myocardin related transcription factor A) Rattus norvegicus
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Symbol: Mrtfa
Name: myocardin related transcription factor A
CRRD ID: 1304873
Description: Predicted to have several functions, including actin monomer binding activity; leucine zipper domain binding activity; and transcription regulator activity. Involved in regulation of transcription by RNA polymerase II. Localizes to nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 66 and megakaryocytic leukemia. Orthologous to human MRTFA (myocardin related transcription factor A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: MODEL
Also known as: basic, SAP, and coiled-coil domain containing protein; BSAC; FLMKL1; LOC315151; megakaryoblastic leukemia (translocation) 1; megakaryoblastic leukemia 1 met; MELODY; MKL/myocardin-like protein 1; Mkl1; MKL1-elongated derivative of yield protein; MKL1met; Mrtf-a
Orthologs:
Homo sapiens (human) : MRTFA (myocardin related transcription factor A)  HGNC  Alliance
Mus musculus (house mouse) : Mrtfa (myocardin related transcription factor A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mrtfa (myocardin related transcription factor A)
Pan paniscus (bonobo/pygmy chimpanzee) : MRTFA (myocardin related transcription factor A)
Canis lupus familiaris (dog) : MRTFA (myocardin related transcription factor A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mrtfa (myocardin related transcription factor A)
Sus scrofa (pig) : MRTFA (myocardin related transcription factor A)
Chlorocebus sabaeus (African green monkey) : MRTFA (myocardin related transcription factor A)
Heterocephalus glaber (naked mole-rat) : Mrtfa (myocardin related transcription factor A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07122,233,196 - 122,403,661 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7122,234,012 - 122,403,667 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07122,217,533 - 122,387,766 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47119,306,220 - 119,415,012 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17119,340,456 - 119,511,326 (-)NCBI
Celera7108,866,997 - 109,036,998 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mrtfa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304873
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.