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Gene: Nlrc3 (NLR family, CARD domain containing 3) Rattus norvegicus
Symbol: Nlrc3
Name: NLR family, CARD domain containing 3
Description: Predicted to have phosphatidylinositol 3-kinase regulatory subunit binding activity. Predicted to be involved in several processes, including negative regulation of cell population proliferation; negative regulation of cytokine production; and negative regulation of intracellular signal transduction. Predicted to localize to several cellular components, including centriolar satellite; cytosol; and perinuclear region of cytoplasm. Orthologous to human NLRC3 (NLR family CARD domain containing 3); INTERACTS WITH amphetamine; 1,1-dichloroethene (ortholog); aflatoxin B2 (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC287070; NLR family, CARD domain containing 3, pseudogene 1; Nlrc3-ps1; RGD1304902; similar to NOD3
Homo sapiens (human) : NLRC3 (NLR family CARD domain containing 3)  HGNC  Alliance
Mus musculus (house mouse) : Nlrc3 (NLR family, CARD domain containing 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nlrc3 (NLR family CARD domain containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NLRC3 (NLR family CARD domain containing 3)
Canis lupus familiaris (dog) : NLRC3 (NLR family CARD domain containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlrc3 (NLR family CARD domain containing 3)
Sus scrofa (pig) : NLRC3 (NLR family CARD domain containing 3)
Chlorocebus sabaeus (African green monkey) : NLRC3 (NLR family CARD domain containing 3)
Heterocephalus glaber (naked mole-rat) : Nlrc3 (NLR family CARD domain containing 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01011,809,531 - 11,844,184 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1011,810,926 - 11,842,482 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01010,565,817 - 10,600,272 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41011,828,972 - 11,850,949 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11011,830,270 - 11,850,949 (+)NCBI
Celera1010,507,188 - 10,541,841 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nlrc3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304902
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.