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Gene: Nup214 (nucleoporin 214) Rattus norvegicus
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Symbol: Nup214
Name: nucleoporin 214
Description: Exhibits nuclear localization sequence binding activity. Involved in mitotic cell cycle. Localizes to the nuclear envelope. Human ortholog(s) of this gene implicated in acute myeloid leukemia and precursor lymphoblastic lymphoma/leukemia. Orthologous to human NUP214 (nucleoporin 214); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; mRNA nuclear export pathway; NXF1-NXT1 export pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; valproic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC296634; nuclear pore complex protein Nup214; nucleoporin 214kDa; RGD1304977; similar to mKIAA0023 protein
Orthologs:
Homo sapiens (human) : NUP214 (nucleoporin 214)  HGNC  Alliance
Mus musculus (house mouse) : Nup214 (nucleoporin 214)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nup214 (nucleoporin 214)
Pan paniscus (bonobo/pygmy chimpanzee) : NUP214 (nucleoporin 214)
Canis lupus familiaris (dog) : NUP214 (nucleoporin 214)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nup214 (nucleoporin 214)
Sus scrofa (pig) : NUP214 (nucleoporin 214)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0310,993,584 - 11,070,638 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.039,227,869 - 9,236,878 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0314,588,337 - 14,597,175 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0316,351,780 - 16,423,232 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,079,165 - 11,165,173 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1310,975,349 - 11,062,057 (+)NCBI
Celera310,002,669 - 10,087,697 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nup214
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304977
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.