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Gene: Usp8 (ubiquitin specific peptidase 8) Rattus norvegicus
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Symbol: Usp8
Name: ubiquitin specific peptidase 8
Description: Predicted to have thiol-dependent ubiquitin-specific protease activity. Involved in cellular response to dexamethasone stimulus; cellular response to nerve growth factor stimulus; and regulation of protein catabolic process at postsynapse, modulating synaptic transmission. Localizes to several cellular components, including the dendritic spine; glutamatergic synapse; and postsynaptic density. Colocalizes with the early endosome. Human ortholog(s) of this gene implicated in ACTH-secreting pituitary adenoma. Orthologous to human USP8 (ubiquitin specific peptidase 8); PARTICIPATES IN mitochondrial autophagy pathway; endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 2,4,6-trinitrobenzenesulfonic acid; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC296121; ubiquitin carboxyl-terminal hydrolase 8; ubiquitin specific protease 8
Orthologs:
Homo sapiens (human) : USP8 (ubiquitin specific peptidase 8)  HGNC  Alliance
Mus musculus (house mouse) : Usp8 (ubiquitin specific peptidase 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Usp8 (ubiquitin specific peptidase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : USP8 (ubiquitin specific peptidase 8)
Canis lupus familiaris (dog) : USP8 (ubiquitin specific peptidase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Usp8 (ubiquitin specific peptidase 8)
Sus scrofa (pig) : USP8 (ubiquitin specific peptidase 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03119,173,818 - 119,222,499 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,173,818 - 119,222,484 (+)Ensembl
Rnor_5.03125,699,400 - 125,747,055 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,237,065 - 114,284,543 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13114,103,490 - 114,189,451 (+)NCBI
Celera3112,804,623 - 112,852,132 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Usp8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1304979
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.