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Gene: Nrl (neural retina leucine zipper) Rattus norvegicus
Symbol: Nrl
Name: neural retina leucine zipper
CRRD ID: 1305197
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; leucine zipper domain binding activity; and promoter-specific chromatin binding activity. Predicted to be involved in positive regulation of rhodopsin gene expression; positive regulation of transcription by RNA polymerase II; and retinal rod cell development. Predicted to localize to cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 27. Orthologous to human NRL (neural retina leucine zipper); INTERACTS WITH 6-propyl-2-thiouracil; all-trans-retinoic acid; bisphenol A.
Type: protein-coding
Also known as: LOC290221; neural retina leucine zipper gene ; neural retina-specific leucine zipper protein
Homo sapiens (human) : NRL (neural retina leucine zipper)  HGNC  Alliance
Mus musculus (house mouse) : Nrl (neural retina leucine zipper gene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrl (neural retina leucine zipper)
Pan paniscus (bonobo/pygmy chimpanzee) : NRL (neural retina leucine zipper)
Canis lupus familiaris (dog) : NRL (neural retina leucine zipper)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrl (neural retina leucine zipper)
Sus scrofa (pig) : NRL (neural retina leucine zipper)
Chlorocebus sabaeus (African green monkey) : NRL (neural retina leucine zipper)
Heterocephalus glaber (naked mole-rat) : Nrl (neural retina leucine zipper)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01534,197,115 - 34,201,408 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,197,193 - 34,198,921 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,087,364 - 38,108,942 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,649,927 - 33,656,045 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11533,667,545 - 33,669,274 (-)NCBI
Celera1528,584,069 - 28,585,797 (-)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nrl
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305197
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.