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Gene: Mcm8 (minichromosome maintenance 8 homologous recombination repair factor) Rattus norvegicus
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Symbol: Mcm8
Name: minichromosome maintenance 8 homologous recombination repair factor
Description: Predicted to have several functions, including DNA binding activity; enzyme binding activity; and mismatch repair complex binding activity. Predicted to be involved in several processes, including DNA metabolic process; gamete generation; and protein stabilization. Predicted to localize to the MCM8-MCM9 complex and nucleoplasm. Human ortholog(s) of this gene implicated in premature ovarian failure. Orthologous to human MCM8 (minichromosome maintenance 8 homologous recombination repair factor); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA helicase MCM8; DNA replication licensing factor MCM8; LOC296178; minichromosome maintenance 8; minichromosome maintenance complex component 8; minichromosome maintenance deficient 8; minichromosome maintenance deficient 8 (S. cerevisiae)
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03125,470,499 - 125,500,795 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03131,954,303 - 131,984,573 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43120,614,429 - 120,644,673 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13120,520,853 - 120,549,803 (+)NCBI
Celera3118,872,729 - 118,902,973 (+)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mcm8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305218
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.