Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ror2 (receptor tyrosine kinase-like orphan receptor 2) Rattus norvegicus
Symbol: Ror2
Name: receptor tyrosine kinase-like orphan receptor 2
Description: Predicted to have several functions, including Wnt-protein binding activity; frizzled binding activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in several processes, including positive regulation of glutamatergic synaptic transmission; positive regulation of macrophage differentiation; and positive regulation of protein serine/threonine kinase activity. Localizes to several cellular components, including dendrite; microtubule; and neuronal cell body. Human ortholog(s) of this gene implicated in autosomal recessive Robinow syndrome; brachydactyly type B1; and cleft palate. Orthologous to human ROR2 (receptor tyrosine kinase like orphan receptor 2); PARTICIPATES IN Wnt signaling, non-canonical pathway; INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
Also known as: LOC306782; tyrosine-protein kinase transmembrane receptor ROR2
Homo sapiens (human) : ROR2 (receptor tyrosine kinase like orphan receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Ror2 (receptor tyrosine kinase-like orphan receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Canis lupus familiaris (dog) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
Sus scrofa (pig) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Chlorocebus sabaeus (African green monkey) : ROR2 (receptor tyrosine kinase like orphan receptor 2)
Heterocephalus glaber (naked mole-rat) : Ror2 (receptor tyrosine kinase like orphan receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01711,953,552 - 12,134,386 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1711,953,552 - 12,134,386 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01714,049,344 - 14,228,982 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41717,735,999 - 17,917,032 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11717,736,906 - 17,919,811 (-)NCBI
Celera1711,736,765 - 11,913,446 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Ror2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305275
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.