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Gene: Mars (methionyl-tRNA synthetase) Rattus norvegicus
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Symbol: Mars
Name: methionyl-tRNA synthetase
Description: Predicted to have methionine-tRNA ligase activity. Predicted to be involved in several processes, including cellular macromolecule biosynthetic process; cellular response to growth factor stimulus; and positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Localizes to the aminoacyl-tRNA synthetase multienzyme complex. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2U. Orthologous to human MARS (methionyl-tRNA synthetase); PARTICIPATES IN glycine N-methyltransferase deficiency pathway; homocystinuria pathway; hypermethioninemia pathway; INTERACTS WITH 1-naphthyl isothiocyanate; bisphenol A; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC299851; methionine--tRNA ligase, cytoplasmic; methionine-tRNA synthetase
Orthologs:
Homo sapiens (human) : MARS (methionyl-tRNA synthetase)  HGNC  Alliance
Mus musculus (house mouse) : Mars (methionine-tRNA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mars (methionyl-tRNA synthetase)
Pan paniscus (bonobo/pygmy chimpanzee) : MARS (methionyl-tRNA synthetase)
Canis lupus familiaris (dog) : MARS (methionyl-tRNA synthetase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mars (methionyl-tRNA synthetase)
Sus scrofa (pig) : MARS (methionyl-tRNA synthetase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0770,585,011 - 70,602,425 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0770,759,159 - 70,776,559 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,252,510 - 67,269,807 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1767,273,245 - 67,290,584 (-)NCBI
Celera760,261,413 - 60,278,690 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mars
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305321
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.