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Gene: Spry4 (sprouty RTK signaling antagonist 4) Rattus norvegicus
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Symbol: Spry4
Name: sprouty RTK signaling antagonist 4
Description: Predicted to be involved in cellular response to leukemia inhibitory factor and negative regulation of signal transduction. Predicted to localize to the cytosol. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 17 with or without anosmia. Orthologous to human SPRY4 (sprouty RTK signaling antagonist 4); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC291610; sprouty homolog 4; sprouty homolog 4 (Drosophila)
Orthologs:
Homo sapiens (human) : SPRY4 (sprouty RTK signaling antagonist 4)  HGNC  Alliance
Mus musculus (house mouse) : Spry4 (sprouty RTK signaling antagonist 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spry4 (sprouty RTK signaling antagonist 4)
Pan paniscus (bonobo/pygmy chimpanzee) : SPRY4 (sprouty RTK signaling antagonist 4)
Canis lupus familiaris (dog) : SPRY4 (sprouty RTK signaling antagonist 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spry4 (sprouty RTK signaling antagonist 4)
Sus scrofa (pig) : SPRY4 (sprouty RTK signaling antagonist 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01832,593,370 - 32,609,890 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1832,594,958 - 32,609,864 (+)Ensembl
Rnor_5.01832,271,207 - 32,287,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41831,532,680 - 31,547,586 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11831,561,542 - 31,563,842 (-)NCBI
Celera1830,074,673 - 30,089,579 (-)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Spry4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305324
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.