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Gene: Sox17 (SRY-box transcription factor 17) Rattus norvegicus
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Symbol: Sox17
Name: SRY-box transcription factor 17
Description: Predicted to have several functions, including DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and beta-catenin binding activity. Predicted to be involved in several processes, including circulatory system development; embryonic morphogenesis; and negative regulation of Wnt signaling pathway. Predicted to localize to nuclear transcription factor complex. Biomarker of cholangiocarcinoma. Human ortholog(s) of this gene implicated in vesicoureteral reflux. Orthologous to human SOX17 (SRY-box transcription factor 17); PARTICIPATES IN Wnt signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; benzo[a]pyrene; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC312936; SRY (sex determining region Y)-box 17; SRY box 17; SRY-box containing gene 17; transcription factor SOX-17
Orthologs:
Homo sapiens (human) : SOX17 (SRY-box transcription factor 17)  HGNC  Alliance
Mus musculus (house mouse) : Sox17 (SRY (sex determining region Y)-box 17)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox17 (SRY-box transcription factor 17)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX17 (SRY-box transcription factor 17)
Canis lupus familiaris (dog) : SOX17 (SRY-box transcription factor 17)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox17 (SRY-box transcription factor 17)
Sus scrofa (pig) : SOX17 (SRY-box transcription factor 17)
Chlorocebus sabaeus (African green monkey) : SOX17 (SRY-box transcription factor 17)
Heterocephalus glaber (naked mole-rat) : Sox17 (SRY-box transcription factor 17)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0514,890,318 - 14,895,907 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl514,890,408 - 14,895,907 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0519,675,563 - 19,681,084 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4515,241,405 - 15,246,904 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1515,244,440 - 15,246,899 (+)NCBI
Celera514,398,084 - 14,403,591 (+)NCBICelera
Cytogenetic Map5q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Sox17
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305371
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.