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Gene: Kdm5a (lysine demethylase 5A) Rattus norvegicus
Symbol: Kdm5a
Name: lysine demethylase 5A
CRRD ID: 1305429
Description: Predicted to have several functions, including DNA binding activity; histone demethylase activity (H3-K4 specific); and transcription coactivator activity. Involved in histone H3-K4 demethylation; male gonad development; and spermatogenesis. Predicted to localize to histone methyltransferase complex and protein-DNA complex. Biomarker of cryptorchidism. Human ortholog(s) of this gene implicated in ankylosing spondylitis. Orthologous to human KDM5A (lysine demethylase 5A); PARTICIPATES IN histone modification pathway; INTERACTS WITH acrylamide; bisphenol A; chloroprene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Jarid1a; jumonji, AT rich interactive domain 1A (Rbp2 like); LOC297563; lysine (K)-specific demethylase 5A; lysine-specific demethylase 5A; MGC189432
Homo sapiens (human) : KDM5A (lysine demethylase 5A)  HGNC  Alliance
Mus musculus (house mouse) : Kdm5a (lysine (K)-specific demethylase 5A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm5a (lysine demethylase 5A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM5A (lysine demethylase 5A)
Canis lupus familiaris (dog) : KDM5A (lysine demethylase 5A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm5a (lysine demethylase 5A)
Sus scrofa (pig) : KDM5A (lysine demethylase 5A)
Chlorocebus sabaeus (African green monkey) : KDM5A (lysine demethylase 5A)
Heterocephalus glaber (naked mole-rat) : Kdm5a (lysine demethylase 5A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04152,892,388 - 152,972,196 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4152,892,388 - 152,972,201 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04219,981,483 - 220,059,803 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44156,736,343 - 156,811,991 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14156,985,211 - 156,990,428 (+)NCBI
Celera4142,417,987 - 142,495,287 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Kdm5a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305429
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.