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Gene: Ppm1d (protein phosphatase, Mg2+/Mn2+ dependent, 1D) Rattus norvegicus
Symbol: Ppm1d
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1D
CRRD ID: 1305460
Description: Predicted to have mitogen-activated protein kinase binding activity and protein serine/threonine phosphatase activity. Involved in cellular response to starvation. Predicted to localize to cytosol and nucleus. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; p38 MAPK signaling pathway; p53 signaling pathway; INTERACTS WITH bisphenol A; decabromodiphenyl ether; diazinon.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC287585; p53-induced protein phosphatase 1; protein phosphatase 1D; protein phosphatase 1D magnesium-dependent, delta isoform; Wip1
Homo sapiens (human) : PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D)  HGNC  Alliance
Mus musculus (house mouse) : Ppm1d (protein phosphatase 1D magnesium-dependent, delta isoform)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppm1d (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Pan paniscus (bonobo/pygmy chimpanzee) : PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Canis lupus familiaris (dog) : PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppm1d (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Sus scrofa (pig) : PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Chlorocebus sabaeus (African green monkey) : PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Heterocephalus glaber (naked mole-rat) : Ppm1d (protein phosphatase, Mg2+/Mn2+ dependent 1D)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01072,909,550 - 72,945,884 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1072,909,550 - 72,945,884 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01072,813,803 - 72,849,854 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41073,575,506 - 73,612,063 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11073,553,678 - 73,626,442 (+)NCBI
Celera1069,098,036 - 69,134,596 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Ppm1d
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305460
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.