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Gene: Ppm1d (protein phosphatase, Mg2+/Mn2+ dependent, 1D) Rattus norvegicus
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Symbol: Ppm1d
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1D
Description: Predicted to have magnesium-dependent protein serine/threonine phosphatase activity and mitogen-activated protein kinase binding activity. Involved in cellular response to starvation. Predicted to localize to the cytosol and nucleus. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; p38 MAPK signaling pathway; p53 signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; bisphenol A; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC287585; p53-induced protein phosphatase 1; protein phosphatase 1D; protein phosphatase 1D magnesium-dependent, delta isoform; Wip1
Orthologs:
Homo sapiens (human) : PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D)  HGNC  Alliance
Mus musculus (house mouse) : Ppm1d (protein phosphatase 1D magnesium-dependent, delta isoform)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppm1d (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Pan paniscus (bonobo/pygmy chimpanzee) : PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Canis lupus familiaris (dog) : PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppm1d (protein phosphatase, Mg2+/Mn2+ dependent 1D)
Sus scrofa (pig) : PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01072,909,550 - 72,945,884 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01072,813,803 - 72,849,854 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41073,575,506 - 73,612,063 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11073,553,678 - 73,626,442 (+)NCBI
Celera1069,098,036 - 69,134,596 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Ppm1d
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305460
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.