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Gene: Gpt2 (glutamic--pyruvic transaminase 2) Rattus norvegicus
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Symbol: Gpt2
Name: glutamic--pyruvic transaminase 2
CRRD ID: 1305462
Description: Predicted to have L-alanine:2-oxoglutarate aminotransferase activity. Involved in several processes, including cellular response to insulin stimulus; positive regulation of gluconeogenesis; and response to testosterone. Localizes to extracellular space and mitochondrion. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human GPT2 (glutamic--pyruvic transaminase 2); PARTICIPATES IN alanine, aspartate and glutamate metabolic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alanine aminotransferase 2; ALT2; Cc2-5; glutamic pyruvate transaminase (alanine aminotransferase) 2; glutamic pyruvate transaminase 2; glutamic-pyruvate transaminase 2; LOC307759
Orthologs:
Homo sapiens (human) : GPT2 (glutamic--pyruvic transaminase 2)  HGNC  Alliance
Mus musculus (house mouse) : Gpt2 (glutamic pyruvate transaminase (alanine aminotransferase) 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gpt2 (glutamic--pyruvic transaminase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GPT2 (glutamic--pyruvic transaminase 2)
Canis lupus familiaris (dog) : GPT2 (glutamic--pyruvic transaminase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gpt2 (glutamic--pyruvic transaminase 2)
Sus scrofa (pig) : GPT2 (glutamic--pyruvic transaminase 2)
Chlorocebus sabaeus (African green monkey) : GPT2 (glutamic--pyruvic transaminase 2)
Heterocephalus glaber (naked mole-rat) : Gpt2 (glutamic--pyruvic transaminase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01922,599,003 - 22,633,529 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1922,590,881 - 22,632,071 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01933,605,445 - 33,644,015 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41922,884,586 - 22,915,553 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11922,889,411 - 22,920,379 (-)NCBI
Celera1921,389,431 - 21,420,291 (-)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Gpt2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305462
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.