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Gene: Alg8 (ALG8, alpha-1,3-glucosyltransferase) Rattus norvegicus
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Symbol: Alg8
Name: ALG8, alpha-1,3-glucosyltransferase
Description: Predicted to have alpha-1,3-mannosyltransferase activity and dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process and protein N-linked glycosylation via asparagine. Predicted to localize to the endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ih and polycystic liver disease. Orthologous to human ALG8 (ALG8 alpha-1,3-glucosyltransferase); PARTICIPATES IN N-linked glycan biosynthetic pathway; INTERACTS WITH 2,6-dinitrotoluene; bisphenol A; dibutyl phthalate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: asparagine-linked glycosylation 8 homolog (S. cerevisiae, alpha-1,3-glucosyltransferase); asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase); asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog; asparagine-linked glycosylation 8, alpha-1,3-glucosyltransferase homolog (S. cerevisiae); dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; LOC293129; MGC124750; probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
Orthologs:
Homo sapiens (human) : ALG8 (ALG8 alpha-1,3-glucosyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Alg8 (asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alg8 (ALG8 alpha-1,3-glucosyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALG8 (ALG8 alpha-1,3-glucosyltransferase)
Canis lupus familiaris (dog) : ALG8 (ALG8 alpha-1,3-glucosyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alg8 (ALG8 alpha-1,3-glucosyltransferase)
Sus scrofa (pig) : ALG8 (ALG8 alpha-1,3-glucosyltransferase)
Chlorocebus sabaeus (African green monkey) : ALG8 (ALG8 alpha-1,3-glucosyltransferase)
Heterocephalus glaber (naked mole-rat) : Alg8 (ALG8 alpha-1,3-glucosyltransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01162,342,061 - 162,362,139 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1162,342,051 - 162,362,141 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01168,548,585 - 168,568,612 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41154,607,442 - 154,628,227 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11154,685,649 - 154,706,250 (+)NCBI
Celera1149,783,728 - 149,804,235 (+)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Alg8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305468
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.