Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pax2 (paired box 2) Rattus norvegicus
Symbol: Pax2
Name: paired box 2
Description: Predicted to have several functions, including C2H2 zinc finger domain binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including aging; cellular response to epidermal growth factor stimulus; and positive regulation of cell population proliferation. Localizes to lysosome and nucleus. Biomarker of nephroblastoma. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis 7 and renal coloboma syndrome. Orthologous to human PAX2 (paired box 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bis(2-ethylhexyl) phthalate.
Type: protein-coding
Also known as: LOC293992; paired box gene 2; paired box homeotic gene 2; paired box protein 2; paired box protein Pax-2; Pax-2
Homo sapiens (human) : PAX2 (paired box 2)  HGNC  Alliance
Mus musculus (house mouse) : Pax2 (paired box 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pax2 (paired box 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PAX2 (paired box 2)
Canis lupus familiaris (dog) : PAX2 (paired box 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pax2 (paired box 2)
Sus scrofa (pig) : PAX2 (paired box 2)
Chlorocebus sabaeus (African green monkey) : PAX2 (paired box 2)
Heterocephalus glaber (naked mole-rat) : Pax2 (paired box 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01264,493,579 - 264,585,073 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1264,504,591 - 264,583,329 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01271,936,269 - 272,027,514 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41249,804,055 - 249,895,306 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11250,026,899 - 250,155,758 (+)NCBI
Celera1239,428,164 - 239,506,765 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Pax2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305568
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.