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Gene: Zmpste24 (zinc metallopeptidase STE24) Rattus norvegicus
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Symbol: Zmpste24
Name: zinc metallopeptidase STE24
Description: Predicted to have double-stranded DNA binding activity and metalloendopeptidase activity. Predicted to be involved in several processes, including DNA metabolic process; animal organ development; and cellular protein metabolic process. Predicted to localize to the integral component of endoplasmic reticulum membrane; nuclear envelope; and protein-containing complex. Human ortholog(s) of this gene implicated in connective tissue disease and lethal restrictive dermopathy. Orthologous to human ZMPSTE24 (zinc metallopeptidase STE24); INTERACTS WITH bisphenol A; 17alpha-ethynylestradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CAAX prenyl protease 1 homolog; LOC313564; zinc metallopeptidase, STE24 homolog; zinc metallopeptidase, STE24 homolog (S. cerevisiae); zinc metalloproteinase, STE24 homolog; zinc metalloproteinase, STE24 homolog (S. cerevisiae)
Orthologs:
Homo sapiens (human) : ZMPSTE24 (zinc metallopeptidase STE24)  HGNC  Alliance
Mus musculus (house mouse) : Zmpste24 (zinc metallopeptidase, STE24)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zmpste24 (zinc metallopeptidase STE24)
Pan paniscus (bonobo/pygmy chimpanzee) : ZMPSTE24 (zinc metallopeptidase STE24)
Canis lupus familiaris (dog) : ZMPSTE24 (zinc metallopeptidase STE24)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zmpste24 (zinc metallopeptidase STE24)
Sus scrofa (pig) : ZMPSTE24 (zinc metallopeptidase STE24)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05139,982,404 - 140,015,541 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05143,777,121 - 143,808,982 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45141,644,119 - 141,677,211 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15141,649,218 - 141,682,222 (-)NCBI
Celera5133,182,210 - 133,213,802 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Zmpste24
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305570
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.