Gene: Itgb2 (integrin subunit beta 2) Rattus norvegicus
Symbol: Itgb2
Name: integrin subunit beta 2
Description: Exhibits protein heterodimerization activity; contributes to cell adhesion molecule binding activity; involved in several processes, including aging, leukocyte migration, and regulation of cellular biosynthetic process; localizes to the cell surface and plasma membrane; predicted to colocalize with the cytoplasmic region; used to study nephritis and pneumonia; orthologous to human ITGB2 (integrin subunit beta 2); PARTICIPATES IN hypoxia inducible factor pathway; integrin mediated signaling pathway; Entamoebiasis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',4,4'-Tetrabromodiphenyl ether; 2-nitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cd18; CD18 leukocyte adhesion molecule; integrin beta 2; integrin beta-2; integrin, beta 2; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1); integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit); macrophage antigen 1 (mac-1) beta subunit; macrophage antigen 1 (mac-1) beta subunit); MGC116306
Homo sapiens (human) : ITGB2 (integrin subunit beta 2)  HGNC  Alliance
Mus musculus (house mouse) : Itgb2 (integrin beta 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgb2 (integrin subunit beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGB2 (integrin subunit beta 2)
Canis lupus familiaris (dog) : ITGB2 (integrin subunit beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgb2 (integrin subunit beta 2)
Sus scrofa (pig) : ITGB2 (integrin subunit beta 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02011,777,773 - 11,815,647 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02013,944,190 - 13,981,048 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42011,446,521 - 11,485,009 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12011,446,936 - 11,485,236 (-)NCBI
Celera2012,564,941 - 12,601,097 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Itgb2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305581
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.