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Gene: Rag2 (recombination activating 2) Rattus norvegicus
Symbol: Rag2
Name: recombination activating 2
Description: Predicted to have several functions, including methylated histone binding activity; phosphatidylinositol phosphate binding activity; and zinc ion binding activity. Predicted to be involved in several processes, including B cell homeostatic proliferation; immune system development; and positive regulation of organ growth. Predicted to localize to DNA recombinase complex. Human ortholog(s) of this gene implicated in Omenn syndrome; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, Nk cell-positive. Orthologous to human RAG2 (recombination activating 2); PARTICIPATES IN histone modification pathway; primary immunodeficiency pathway; INTERACTS WITH ammonium chloride; copper atom; copper(0).
Type: protein-coding
Also known as: LOC295953; recombination activating gene 2; recombination activating protein 2; V(D)J recombination-activating protein 2
Homo sapiens (human) : RAG2 (recombination activating 2)  HGNC  Alliance
Mus musculus (house mouse) : Rag2 (recombination activating gene 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rag2 (recombination activating 2)
Pan paniscus (bonobo/pygmy chimpanzee) : RAG2 (recombination activating 2)
Canis lupus familiaris (dog) : RAG2 (recombination activating 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rag2 (recombination activating 2)
Sus scrofa (pig) : RAG2 (recombination activating 2)
Chlorocebus sabaeus (African green monkey) : RAG2 (recombination activating 2)
Heterocephalus glaber (naked mole-rat) : Rag2 (recombination activating 2)
more info ...
Allele / Splice: Rag2em2Mcwi   Rag2em3Mcwi   Rag2em1Mcwi   Rag2em1Sage  
Genetic Models: SD-Rag2em1Sage F344-Rag2em1Sage SD-Rag2em3McwiIl2rgem2Mcwi SS-Rag2em1Mcwi SD-Rag2em3Mcwi SD-Rag2em2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0391,191,837 - 91,200,134 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl391,191,837 - 91,200,134 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0397,851,318 - 97,859,615 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4386,764,810 - 86,773,438 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1386,661,236 - 86,668,153 (+)NCBI
Celera387,008,586 - 87,016,420 (+)NCBICelera
Cytogenetic Map3q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Rag2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305588
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.