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Gene: Fbxo7 (F-box protein 7) Rattus norvegicus
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Symbol: Fbxo7
Name: F-box protein 7
Description: Predicted to have several functions, including enzyme binding activity; protein binding activity, bridging involved in substrate recognition for ubiquitination; and protein heterodimerization activity. Involved in negative regulation of neuron death and positive regulation of autophagy of mitochondrion. Predicted to localize to several cellular components, including Lewy body core; Lewy body corona; and Lewy neurite. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 15. Orthologous to human FBXO7 (F-box protein 7); PARTICIPATES IN Parkinson's disease pathway; INTERACTS WITH bisphenol A; furan; glafenine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: F-box only protein 7; LOC366854
Orthologs:
Homo sapiens (human) : FBXO7 (F-box protein 7)  HGNC  Alliance
Mus musculus (house mouse) : Fbxo7 (F-box protein 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo7 (F-box protein 7)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO7 (F-box protein 7)
Canis lupus familiaris (dog) : FBXO7 (F-box protein 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo7 (F-box protein 7)
Sus scrofa (pig) : FBXO7 (F-box protein 7)
Chlorocebus sabaeus (African green monkey) : FBXO7 (F-box protein 7)
Heterocephalus glaber (naked mole-rat) : Fbxo7 (F-box protein 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0723,815,246 - 23,843,505 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl723,815,245 - 23,843,634 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0723,964,601 - 23,993,030 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4719,947,498 - 19,975,730 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1719,960,416 - 19,988,648 (-)NCBI
Celera715,042,489 - 15,070,722 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Fbxo7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305648
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.