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Gene: Grhl1 (grainyhead-like transcription factor 1) Rattus norvegicus
Symbol: Grhl1
Name: grainyhead-like transcription factor 1
Description: Predicted to have DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and protein homodimerization activity. Predicted to be involved in several processes, including desmosome organization; establishment of skin barrier; and regulation of keratinocyte differentiation. Predicted to localize to the Golgi apparatus; cytosol; and nucleoplasm. Orthologous to human GRHL1 (grainyhead like transcription factor 1); INTERACTS WITH cadmium dichloride; thioacetamide; vinclozolin.
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA methyltransferase 3A; grainyhead-like 1; grainyhead-like 1 (Drosophila); grainyhead-like protein 1 homolog; LOC313993
Homo sapiens (human) : GRHL1 (grainyhead like transcription factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Grhl1 (grainyhead like transcription factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grhl1 (grainyhead like transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GRHL1 (grainyhead like transcription factor 1)
Canis lupus familiaris (dog) : GRHL1 (grainyhead like transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grhl1 (grainyhead like transcription factor 1)
Sus scrofa (pig) : GRHL1 (grainyhead like transcription factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0643,734,837 - 43,795,757 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0660,602,932 - 60,668,616 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4642,217,279 - 42,260,621 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1642,132,033 - 42,263,747 (+)NCBI
Celera640,494,932 - 40,542,079 (+)NCBICelera
Cytogenetic Map6q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Grhl1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1305735
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.